The laboratory animal center began operations in 2000 with a small conventional breeding room for laboratory mice in the Tehran Zafaraniyeh neighborhood. This department plays a very important and key role in conducting clinical research at Royan Research Institute by providing general services such as maintenance, breeding, and production of laboratory animals and specialized services including performing various surgeries, paraclinical services (radiology, ultrasound), modeling of various diseases and specialized training of students and supervision of compliance with the ethical principles of working on laboratory animals. In May 2020, this center managed to obtain the ISO 9001:2015 certificate and also successfully passed the first care audit in June 2021.